two dimensional thin layer chromatography on polyamide sheets is a useful method for identification of pth-amino acids which have very close rf-values. the solvent systems described here are particularly effective and have an edge over other solvent systems used for the separation of pth-amino acids. the solvent systems provide a clear separation of all pth-amono acids except lle / leu in a rel...

Flexible forming is a sheet metal forming process with the application of soft material tooling. In this study, flexible (silicone rubber, SR, and styrene butadiene rubber, SBR) and semi-rigid (polyamide 66, PA) polymeric materials were adopted to make several upper dies which were used in combination with aluminium lower dies. Stamping operations were performed on a thin aluminium alloy sheet ...

polyamide 6 has been widely used in food packaging applications and also green tea contains amounts of antioxidant compounds. the aim of this study was investigation of green tea effects on properties of polyamide packaging polymer. polyamide 6 was dissolved in methanol which was saturated with calcium chloride. the active packaging film was produced by incorporation of methanol green tea extra...

Pyrrole-imidazole (PI) polyamide is a novel gene regulating agent that competitively inhibits transcription factor binding to the promoter of the specific target gene. Liver fibrosis is an integral stage in the development of chronic liver disease, and transforming growth factor β (TGFβ) is known to play a central role in the progression of this entity. The aim of this study was to evaluate the...

The fluorescence from tetramethyl rhodamine in hairpin polyamide tetramethyl rhodamine (TMR) conjugates is quenched in solution. TMR fluoresces brightly upon polyamide binding match DNA. Similar behavior is not observed in the presence of mismatch DNA; the hairpin polyamide-fluorophore conjugates therefore provide a smallmolecule fluorescent means for detecting chosen DNA sequences in homogenou...

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a membrane protein that can support the binding, internalization, and proteolytic degradation of oxidized low-density lipoprotein. The LOX-1 expression increases in the neointima after balloon injury. To develop an efficient compound to inhibit LOX-1, we designed and synthesized a novel gene silencer pyrrole-imidazole (PI) polya...

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a membrane protein that can support the binding, internalization, and proteolytic degradation of oxidized low-density lipoprotein. The LOX-1 expression increases in the neointima after balloon injury. To develop an efficient compound to inhibit LOX-1, we designed and synthesized a novel gene silencer pyrrole-imidazole (PI) polya...

Pyrrole-imidazole (Py-Im) polyamides are nuclease-resistant novel compounds that inhibit gene expression by binding to the minor groove of DNA. A Py-Im polyamide that targets rat TGF-beta1 was designed as a gene-silencing agent for progressive renal diseases, and the distribution and the effects of this polyamide on renal injury were examined in Dahl-salt sensitive (Dahl-S) rats. For identifica...

Two dimensional thin layer chromatography on polyamide sheets is a useful method for identification of PTH-amino acids which have very close Rf-values. The solvent systems described here are particularly effective and have an edge over other solvent systems used for the separation of PTH-amino acids. The solvent systems provide a clear separation of all PTH-amono acids except lle / Leu in a...